The DADA2 Case: The Path to Possibility
What is the Path to Possibility?
I have always believed in what’s possible for DADA2 patients – a better quality of life, connection with others, world-class research into the disease, and treatments that could even be curative.
So this month is a little special – we want to introduce Pursuing What’s Possible. This is a first of its kind for the DADA2 Foundation. In it, you will find a little history, a little story, a little detail on our impact – and a whole lot of hope for what is next.
What’s next, however, cannot be reached without a doubling down on our commitment to the power of network and collaboration. So, in the coming months, we’re expanding our networks and we invite you to help. Read on to see the role you can play in expanding partnership, expertise, or financial support.
Until next time,
Chip Chambers, M.D., Founder & President, The DADA2 Foundation
Making the Case for What’s Possible
We’ve talked about it. Now it’s time to read about it.
The Path to Possibility.
This path is our opportunity to Pursue What’s Possible: diagnose DADA2 earlier and treat the disease in a more targeted way. We’ll do that with three milestones of PEG-ADA2, the ADA2 Now Meter, and a Patient Registry. Outlined in this comprehensive Impact & Vision report, we believe this path can lead to immense progress not just for the Foundation but for the care of every DADA2 patient and their family.
We invite you to read this report and share it widely with your networks, friends, family, and physician.
As you share, the DADA2 Foundation is also actively expanding our network to more leaders in the life sciences and philanthropic communities so that we can speed the path toward progress. We recently held two different calls with a group of interested people and organizations.
If you have a network of leaders whose expertise, partnership opportunities, or funding capacities can support the Foundation, we would be happy to share the same presentation with them. Email us at info@dada2.org and we’ll be in touch with more times to hear about this exciting progress.
10 Things We Want People to Know About DADA2
Marking our 10th Anniversary, ten brave DADA2 warriors have joined together to share the ten things they wish people knew about DADA2 – from daily life struggles to the hope we have for a cure.
We invite you to watch each of these videos on our social media platforms – each of which is available to click below. Then, share the posts. Each comes with a little education about DADA2. Who knows? Sharing a post could tell someone about DADA2 who needs to know more so they can spot a patient in their medical practice or support our work! Pick the platform of your choice below! And make sure you are following us on at least one as we share updates.
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Become a Fundraiser this Year
If you would like to support the work of the DADA2 Foundation by being a fundraiser, let us know! We’re setting up fundraising pages this month! Email: info@dada2.org.
Latest Research
Genetic and Functional Activity Analyses of Adenosine Deaminase Type 2 in Patients with Deficiency of Adenosine Deaminase 2. Önen, Merve, et al. TURKISH ARCHIVES OF PEDIATRICS (2026).
Clinically validated assay for rapid determination of type I and type II interferon activity in systemic inflammatory diseases. Lam M et al. Journal of Allergy and Clinical Immunology, 2026; 157, 1411-1422.e12
A Review of Adenosine Deaminase 2 (ADA2) as a Biomarker of Monocyte/Macrophage Activation. Lim, J., Doss, J., Shen, J. et al. Curr Allergy Asthma Rep 26, 2 (2026).
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